Physalis minima, Allium odoratum, Tabebuia chrysantha, Chentotecha longilamina, Impatiens balsamina are plants that chosen to know its anticancer activity. The plant candidates were chosen by study its chemotaxonomy with plants that has close relationship in its chemical compound and its morphological taxonomy. Based on the potency of the floral species in Indonesia, the aim of this research are to get several potential plant for anticancer therapy.
floral species in Indonesia, about 1.260 species has pharmacological activities including anti cancer. In the other word, indonesia has many potential in its natural resources, especially its floral biodiversity that has many potential as natural drugs. As a development country the cancer diseases in indonesia being the sixth disease with high mortality number. At the advance country the cancer is the second disease that causing death after the cardiovascular diseases (Nafrialdi and Sulistia, 2007). Based on World Health Organization in 2005 7,6 million people death by cancer and 84 million people is going to be death 10 years onward (Diananda, 2007).
Background Cancer is still became most dangerous disease in the world. Key Word: anticancer activity, BST, plants 1. And with methanol extract Chentotecha longilamina, Impatiens balsamina, Tabebuia chrysantha.shows the activity each with LC50 908,58 µg / ml, 744,48 µg/ml and 858 µg/ml. With n-Hexane extract of Physalis minima, Allium odoratum, Tabebuia chrysantha has potential biological (anticancancer) activity with LC50 920,92 µg/ml, 805,62 µg/ml, and 652.868 µg/ml. The result from the fiftht plant were tested show various responses. By measuring the LC50 of the several plant extract to the Artemia salina larvae that analogue with the cancer cells.
Brine shrimp lethality test (BST) is the method that used in this study. The aim of this study is to screen several plant candidate for anti cancer therapy.
Indonesia has high biodiversity especially its pharmacologically beneficial flora such as flora with anti cancer activity. Jamil 1 Program Studi Farmasi Fakultas Ilmu Kesehatan Universitas Muhammadiyah Malang email contact: Abstract. Anti Cancer Pre-Screening for Several Plant Using Brine Shrimp Lethality Test Chasanah U 1.
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